東北大学病院 放射線治療科

研究活動について

研究業績 2020年

原著論文

  1. Jingu K, Takahashi N, Murakami Y, Ishikawa K, Itasaka S, Takahashi T, Isohashi F, Sakayauchi T, Ogawa K; JROSG Working Subgroup of Gastrointestinal Cancers. Is Concurrent Chemotherapy With Radiotherapy for Esophageal Cancer Beneficial in Patients Aged 80 Years or Older? Anticancer Res. 2019 Aug;39(8):4279-4283. doi: 10.21873/anticanres.13592. PMID: 31366518.
  2. Toh Y, Numasaki H, Tachimori Y, Uno T, Jingu K, Nemoto K, Matsubara H. Current status of radiotherapy for patients with thoracic esophageal cancer in Japan, based on the Comprehensive Registry of Esophageal Cancer in Japan from 2009 to 2011 by the Japan Esophageal Society. Esophagus. 2020 Jan;17(1):25-32. doi: 10.1007/s10388-019-00690-z. Epub 2019 Aug 31. PMID: 31473871.
  3. Shiga S, Murata Y, Hashimoto T, Urushihara Y, Fujishima Y, Kudo K, Sonohara Y, Kurusu M, Takeda K, Jingu K, Hosoi Y. DNA-PKcs is activated under nutrient starvation and activates Akt, MST1, FoxO3a, and NDR1. Biochem Biophys Res Commun. 2020 Jan 15;521(3):668-673. doi: 10.1016/j.bbrc.2019.10.133. Epub 2019 Nov 1. PMID: 31679687.
  4. Tang L, Matsushita H, Ishikawa Y, Ishida T, Jingu K. A case report and review of the literature: cardiotoxicities after radiotherapy for breast cancer patients with high-risk factors of cardiovascular disease. Int Cancer Conf J. 2019 Oct 8;9(1):41-44. doi: 10.1007/s13691-019-00390-6. PMID: 31950017; PMCID: PMC6942553.
  5. Umezawa R, Ito Y, Wakita A, Nakamura S, Okamoto H, Takahashi K, Inaba K, Murakami N, Igaki H, Jingu K, Itami J. How Much Was the Elective Lymph Node Region Covered in Involved-Field Radiation Therapy for Locally Advanced Pancreatic Cancer? Evaluation of Overlap Between Gross Target Volume and Celiac Artery-Superior Mesenteric Artery Lymph Node Regions. Adv Radiat Oncol. 2019 Sep 13;5(3):377-387. doi: 10.1016/j.adro.2019.08.014. PMID: 32529131; PMCID: PMC7278027.
  6. Kadoya N, Abe K, Nemoto H, Sato K, Ieko Y, Ito K, Dobashi S, Takeda K, Jingu K. Evaluation of a 3D-printed heterogeneous anthropomorphic head and neck phantom for patient-specific quality assurance in intensity-modulated radiation therapy. Radiol Phys Technol. 2019 Sep;12(3):351-356. doi: 10.1007/s12194-019-00527-5. Epub 2019 Jul 30. PMID: 31364005.
  7. Murakami Y, Kenjo M, Ishikawa K, Sakayauchi T, Itasaka S, Negoro Y, Jingu K, Nishimura Y, Nagata Y, Ogawa K. Risk factors for severe gastrointestinal toxicity in patients receiving palliative radiotherapy for metastatic bone tumors: association with the use of molecular-targeted agents. J Radiat Res. 2020 Jul 6;61(4):629-634. doi: 10.1093/jrr/rraa035. PMID: 32567666; PMCID: PMC7336816.
  8. Sato Y, Jingu K, Umezawa R, Yamamoto T, Ishikawa Y, Takeda K, Suzuki Y, Matsushita H. A long-term survival case following salvage stereotactic radiotherapy for local recurrence after definitive chemoradiotherapy for stage III non-small cell lung cancer. Int Cancer Conf J. 2020 Jul 3;9(4):227-230. doi: 10.1007/s13691-020-00431-5. PMID: 32904079; PMCID: PMC7450021.
  9. Yamamoto T, Umezawa R, Tokunaga H, Kubozono M, Kozumi M, Takahashi N, Matsushita H, Kadoya N, Ito K, Sato K, Tsuji K, Shimada M, Jingu K. Clinical experience of pelvic radiotherapy or chemoradiotherapy for postoperative uterine cervical cancer using intensity-modulated radiation therapy. J Radiat Res. 2020 May 22;61(3):470-478. doi: 10.1093/jrr/rraa004. PMID: 32100833; PMCID: PMC7299262.
  10. Miyasaka Y, Kadoya N, Ito K, Umezawa R, Kubozono M, Yamamoto T, Nakajima Y, Saito M, Takayama Y, Nemoto K, Iwai T, Jingu K. Quantitative analysis of intra-fractional variation in CT-based image guided brachytherapy for cervical cancer patients. Phys Med. 2020 May;73:164-172. doi: 10.1016/j.ejmp.2020.04.009. Epub 2020 Apr 30. PMID: 32361574.
  11. Tang L, Ishikawa Y, Matsushita H, Jingu K. Prognostic value of the AJCC 8th edition staging system for Japanese patients treated with surgery followed by radiotherapy for breast cancer. Int J Clin Oncol. 2020 Aug;25(8):1499-1505. doi: 10.1007/s10147-020-01686-x. Epub 2020 Apr 30. PMID: 32356049.
  12. Takagi H, Kadoya N, Kajikawa T, Tanaka S, Takayama Y, Chiba T, Ito K, Dobashi S, Takeda K, Jingu K. Multi-atlas-based auto-segmentation for prostatic urethra using novel prediction of deformable image registration accuracy. Med Phys. 2020 Jul;47(7):3023-3031. doi: 10.1002/mp.14154. Epub 2020 Apr 27. PMID: 32201958.
  13. Kimura Y, Kadoya N, Tomori S, Oku Y, Jingu K. Error detection using a convolutional neural network with dose difference maps in patient-specific quality assurance for volumetric modulated arc therapy. Phys Med. 2020 May;73:57-64. doi: 10.1016/j.ejmp.2020.03.022. Epub 2020 Apr 21. PMID: 32330812.
  14. Parishan M, Faghihi R, Kadoya N, Jingu K. The effects of a transverse magnetic field on the dose enhancement of nanoparticles in a proton beam: a Monte Carlo simulation. Phys Med Biol. 2020 Apr 17;65(8):085002. doi: 10.1088/1361-6560/ab7a70. PMID: 32101796.
  15. Yamamoto T, Niibe Y, Matsumoto Y, Dekura Y, Oh RJ, Yamashita H, Kakuhara H, Aoki M, Jingu K. Stereotactic Body Radiotherapy for Pulmonary Oligometastases from Esophageal Cancer: Results and Prognostic Factors. Anticancer Res. 2020 Apr;40(4):2065-2072. doi: 10.21873/anticanres.14164. PMID: 32234898.
  16. Yamamoto T, Niibe Y, Yamada K, Aoki M, Onishi H, Katsui K, Dekura Y, Nishikawa A, Manabe Y, Yamashita H, Jingu K. Significant reduction of oncologic pulmonary death by local control for pulmonary oligometastases treated with stereotactic body radiotherapy. Radiother Oncol. 2020 Jun;147:86-91. doi: 10.1016/j.radonc.2020.03.019. Epub 2020 Mar 26. PMID: 32247205.
  17. Nakajima Y, Kadoya N, Kimura T, Hioki K, Jingu K, Yamamoto T. Variations Between Dose-Ventilation and Dose-Perfusion Metrics in Radiation Therapy Planning for Lung Cancer. Adv Radiat Oncol. 2020 Mar 20;5(3):459-465. doi: 10.1016/j.adro.2020.03.002. PMID: 32529141; PMCID: PMC7280081.
  18. Kadoya N, Tanaka S, Kajikawa T, Tanabe S, Abe K, Nakajima Y, Yamamoto T, Takahashi N, Takeda K, Dobashi S, Takeda K, Nakane K, Jingu K. Homology-based radiomic features for prediction of the prognosis of lung cancer based on CT-based radiomics. Med Phys. 2020 Jun;47(5):2197-2205. doi: 10.1002/mp.14104. Epub 2020 Mar 16. PMID: 32096876.
  19. Jingu K, Numasaki H, Toh Y, Nemoto K, Uno T, Doki Y, Matsubara H. Chemoradiotherapy and radiotherapy alone in patients with esophageal cancer aged 80 years or older based on the Comprehensive Registry of Esophageal Cancer in Japan. Esophagus. 2020 Jul;17(3):223-229. doi: 10.1007/s10388-020-00725-w. Epub 2020 Feb 22. PMID: 32088786.
  20. Nemoto K, Kawashiro S, Toh Y, Numasaki H, Tachimori Y, Uno T, Jingu K, Matsubara H. Comparison of the effects of radiotherapy doses of 50.4 Gy and 60 Gy on outcomes of chemoradiotherapy for thoracic esophageal cancer: subgroup analysis based on the Comprehensive Registry of Esophageal Cancer in Japan from 2009 to 2011 by the Japan Esophageal Society. Esophagus. 2020 Apr;17(2):122-126. doi: 10.1007/s10388-019-00711-x. Epub 2020 Jan 7. PMID: 31912332; PMCID: PMC7066307.
  21. Kadoya N, Abe K, Nemoto H, Sato K, Ieko Y, Ito K, Dobashi S, Takeda K, Jingu K. [Evaluation of a 3D-printed heterogeneous anthropomorphic head and neck phantom for patient-specific quality assurance in intensity modulated radiation therapy]. Igaku Butsuri. 2020;40(3):109. Japanese. doi: 10.11323/jjmp.40.3_109. PMID: 32999249.
  22. Nakajima Y, Kadoya N, Kanai T, Saito M, Kito S, Hashimoto S, Karasawa K, Jingu K. Evaluation of the effect of user-guided deformable image registration of thoracic images on registration accuracy among users. Med Dosim. 2020 Autumn;45(3):206-212. doi: 10.1016/j.meddos.2019.12.004. Epub 2020 Jan 31. PMID: 32014379.
  23. Niibe Y, Yamamoto T, Onishi H, Yamashita H, Katsui K, Matsumoto Y, Oh RJ, Aoki M, Shintani T, Yamada K, Kobayashi M, Ozaki M, Manabe Y, Yahara K, Nishikawa A, Kakuhara H, Yamamoto K, Inoue T, Takada YU, Nagata K, Suzuki O, Terahara A, Jingu K. Pulmonary Oligometastases Treated by Stereotactic Body Radiation Therapy: A Nationwide Survey of 1,378 Patients. Anticancer Res. 2020 Jan;40(1):393-399. doi: 10.21873/anticanres.13965. PMID: 31892592.

国際学会発表

  1. Long-Term Change in The Oral QOL of Patients Treated with Radiotherapy for Head and Neck Cancer: Comparison of the Effects of IMRT and 3D-CRT. K. Jingu, N. Takahashi, S. Tasaka, R. Umezawa, T. Yamamoto, Y. Ishikawa, et al. ASTRO 2020 annual meeting (web), poster
  2. Radiotherapy for Esophageal Cancer in Patients ≥80 years: A Retrospective Study in a Single Institution. N. Takahashi, R. Umezawa, K. Kishida, H. Matsushita, T. Yamamoto, Y. Ishikawa, et al. ASTRO 2020 annual meeting (web), poster
  3. Outcomes Of Radiation Therapy For Clinically Node-Positive Prostate Cancer: Surveillance Study Of The Japanese Radiation Oncology Study Group (JROSG). T. Maebayashi, T. Mizowaki, K. Nakamura, K. Nakamura, K. Inaba, H. Asakura, K. Jingu, et al. ASTRO 2020 annual meeting (web), poster
  4. Clinical Predictors Of Severe Late Urinary Toxicity After Curative Intensity-Modulated Radiation Therapy For Localized Prostate Cancer. K. Takeda, R. Umezawa, Y. Ishikawa, T. Yamamoto, N. Takahashi, K. Takeda, et al. ASTRO 2020 annual meeting (web), poster
  5. Prevention of oncologic pulmonary death by control for pulmonary oligometastases treated with SBRT. T. Yamamoto, N. Yuzuru, K. Yamada, M. Aoki, H. Onishi, K. Katsui, et al. ESTRO 2020 annual meeting (web), poster
  6. Clinical experience of pelvic radiotherapy for postoperative uterine cervical cancer using VMAT. T. Yamamoto, R. Umezawa, M. Kubozono, H. Tokunaga, H. Matsushita, Y. Ishikawa, et al. ESTRO 2020 annual meeting (web), poster
  7. Preliminary results of SRS for a lung tumor: a single-arm phase 2 study in a single institute. T. Yamamoto, N. Kadoya, H. Matsushita, R. Umezawa, K. Ito, Y. Ishikawa, et al. ESTRO 2020 annual meeting (web), poster

総論

  1. 角谷 倫之, 松田 匠平, 竹内 孝至, 梶川 智博, 田中 祥平, 田邊 俊平, 勝田 義之, 伊藤 謙吾, 神宮 啓一. AIと放射線治療. 臨床放射線 65(2), 163-171, 2020-02.
  2. 神宮 啓一. 頭頸部がんの最新診療 最新の頭頸部がんの放射線治療(解説/特集). 日本医師会雑誌148(6), 1099-1102, 2019.

受賞

  1. 神宮啓一 日本放射線腫瘍学会 第4回優秀査読者賞
  2. 角谷倫之 Radiological Physics and Technology 土井賞(優秀論文賞)2019年